ENSMUSG00000052160


Mus musculus

Features
Gene ID: ENSMUSG00000052160
  
Biological name :Pld4
  
Synonyms : Phospholipase D4 / Pld4 / Q8BG07
  
Possible biological names infered from orthology : phospholipase D family member 4 / Q96BZ4
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F1
Gene start: 112760655
Gene end: 112768990
  
Corresponding Affymetrix probe sets: 10398907 (MoGene1.0st)   1433678_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000067002
NCBI entrez gene - 104759     See in Manteia.
MGI - MGI:2144765
RefSeq - NM_178911
RefSeq Peptide - NP_849242
swissprot - Q8BG07
Ensembl - ENSMUSG00000052160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLD4ENSGALG00000011646Gallus gallus
 PLD4ENSG00000166428Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pld3 / O35405 / Phospholipase D3 / Q8IV08* / phospholipase D family member 3*ENSMUSG0000000336341
Pld5 / Q3UNN8 / Mus musculus phospholipase D family, member 5 (Pld5), transcript variant 3, mRNA. / Q8N7P1* / phospholipase D family member 5*ENSMUSG0000005521430


Protein motifs (from Interpro)
Interpro ID Name
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR032803  PLD-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006909 phagocytosis IMP
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane IDA
 cellular_componentGO:0045335 phagocytic vesicle IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004630 phospholipase D activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol
Role of phospholipids in phagocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
Show

Allelic Composition: Esr1tm1.1Ohl/Esr1tm1.1Ohl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Esr1tm1.1Ohl/Esr1tm1.1Ohl
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Pld4mpc96H/Pld4mpc96H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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