ENSMUSG00000003363


Mus musculus

Features
Gene ID: ENSMUSG00000003363
  
Biological name :Pld3
  
Synonyms : O35405 / Phospholipase D3 / Pld3
  
Possible biological names infered from orthology : phospholipase D family member 3 / Q8IV08
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 27532000
Gene end: 27553218
  
Corresponding Affymetrix probe sets: 10561306 (MoGene1.0st)   1416013_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122897
Ensembl peptide - ENSMUSP00000113820
Ensembl peptide - ENSMUSP00000115891
Ensembl peptide - ENSMUSP00000119228
Ensembl peptide - ENSMUSP00000112942
NCBI entrez gene - 18807     See in Manteia.
MGI - MGI:1333782
RefSeq - XM_017322042
RefSeq - NM_011116
RefSeq - XM_006539642
RefSeq - XM_006539643
RefSeq - XM_006539645
RefSeq - XM_006539646
RefSeq - XM_011250456
RefSeq - NM_001317355
RefSeq Peptide - NP_001304284
RefSeq Peptide - NP_035246
swissprot - D6RCG9
swissprot - D3Z179
swissprot - O35405
swissprot - D3YY25
Ensembl - ENSMUSG00000003363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pld3ENSDARG00000068199Danio rerio
 PLD3ENSG00000105223Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pld4 / Q8BG07 / Phospholipase D4 / Q96BZ4* / phospholipase D family member 4*ENSMUSG0000005216042
Pld5 / Q3UNN8 / Mus musculus phospholipase D family, member 5 (Pld5), transcript variant 3, mRNA. / Q8N7P1* / phospholipase D family member 5*ENSMUSG0000005521433


Protein motifs (from Interpro)
Interpro ID Name
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR032803  PLD-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004630 phospholipase D activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IEA


Pathways (from Reactome)
Pathway description
Role of phospholipids in phagocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0008040 decreased NK T cell number "reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0008211 decreased mature B cell number "reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0008346 increased gamma-delta T cell number "greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

 MP:0010067 increased red blood cell distribution width "higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]
Show

Allelic Composition: Cidectm1.1Gonz/Cidectm1.2Gonz,Tg(Fabp4-cre)#Abel/?
Genetic Background: B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr