ENSG00000166743


Homo sapiens

Features
Gene ID: ENSG00000166743
  
Biological name :ACSM1
  
Synonyms : ACSM1 / acyl-CoA synthetase medium chain family member 1 / Q08AH1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.3
Gene start: 20623237
Gene end: 20698890
  
Corresponding Affymetrix probe sets: 215432_at (Human Genome U133 Plus 2.0 Array)   234197_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301956
Ensembl peptide - ENSP00000428098
Ensembl peptide - ENSP00000428650
Ensembl peptide - ENSP00000428830
Ensembl peptide - ENSP00000428047
NCBI entrez gene - 116285     See in Manteia.
OMIM - 614357
RefSeq - XM_017022915
RefSeq - XM_006721018
RefSeq - XM_011545729
RefSeq - XM_011545730
RefSeq - XM_011545731
RefSeq - XM_011545732
RefSeq - NM_001318890
RefSeq - NM_052956
RefSeq - XM_006721016
RefSeq - XM_006721017
RefSeq Peptide - NP_001305819
RefSeq Peptide - NP_443188
swissprot - H0YAU5
swissprot - Q08AH1
swissprot - E5RFK0
Ensembl - ENSG00000166743
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029827Gallus gallus
 Acsm1ENSMUSG00000033533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACSM4 / P0C7M7 / acyl-CoA synthetase medium chain family member 4ENSG0000021500955
ACSM2B / Q68CK6 / acyl-CoA synthetase medium chain family member 2BENSG0000006681355
ACSM5 / Q6NUN0 / acyl-CoA synthetase medium chain family member 5ENSG0000018354955
ACSM2A / Q08AH3 / acyl-CoA synthetase medium chain family member 2AENSG0000018374755
ACSM3 / Q53FZ2 / acyl-CoA synthetase medium chain family member 3ENSG0000000518753
ACSM6 / Q6P461 / acyl-CoA synthetase medium chain family member 6ENSG0000017312434
ACSS1 / Q9NUB1 / acyl-CoA synthetase short chain family member 1ENSG0000015493027
ACSS2 / Q9NR19 / acyl-CoA synthetase short chain family member 2ENSG0000013106927
ACSS3 / Q9H6R3 / acyl-CoA synthetase short chain family member 3ENSG0000011105825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process IBA
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0015980 energy derivation by oxidation of organic compounds NAS
 biological_processGO:0018874 benzoate metabolic process NAS
 biological_processGO:0019395 fatty acid oxidation NAS
 biological_processGO:0019605 butyrate metabolic process NAS
 biological_processGO:0042632 cholesterol homeostasis NAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003996 acyl-CoA ligase activity IDA
 molecular_functionGO:0004321 fatty-acyl-CoA synthase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0015645 fatty acid ligase activity IBA
 molecular_functionGO:0016405 CoA-ligase activity TAS
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047760 butyrate-CoA ligase activity IEA


Pathways (from Reactome)
Pathway description
Conjugation of benzoate with glycine
Conjugation of phenylacetate with glutamine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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