ENSG00000131069


Homo sapiens

Features
Gene ID: ENSG00000131069
  
Biological name :ACSS2
  
Synonyms : ACSS2 / acyl-CoA synthetase short chain family member 2 / Q9NR19
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.22
Gene start: 34872146
Gene end: 34927962
  
Corresponding Affymetrix probe sets: 234312_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418608
Ensembl peptide - ENSP00000418362
Ensembl peptide - ENSP00000418812
Ensembl peptide - ENSP00000420351
Ensembl peptide - ENSP00000420105
Ensembl peptide - ENSP00000419925
Ensembl peptide - ENSP00000419167
Ensembl peptide - ENSP00000253382
Ensembl peptide - ENSP00000353804
Ensembl peptide - ENSP00000417783
Ensembl peptide - ENSP00000418152
NCBI entrez gene - 55902     See in Manteia.
OMIM - 605832
RefSeq - XM_011528912
RefSeq - NM_001076552
RefSeq - NM_001242393
RefSeq - NM_018677
RefSeq - XM_005260455
RefSeq - XM_005260456
RefSeq - XM_006723826
RefSeq - XM_011528905
RefSeq - XM_011528906
RefSeq - XM_011528907
RefSeq - XM_011528908
RefSeq - XM_011528909
RefSeq - XM_011528911
RefSeq Peptide - NP_001229322
RefSeq Peptide - NP_061147
RefSeq Peptide - NP_001070020
swissprot - C9J7L5
swissprot - C9IYL0
swissprot - F8WBQ7
swissprot - F8WC73
swissprot - F8WCJ4
swissprot - F8WDJ9
swissprot - B4DEH9
swissprot - Q9NR19
swissprot - C9JY31
swissprot - C9JXD9
Ensembl - ENSG00000131069
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acss2ENSDARG00000037781Danio rerio
 ACSS2ENSGALG00000003362Gallus gallus
 Acss2ENSMUSG00000027605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACSS1 / Q9NUB1 / acyl-CoA synthetase short chain family member 1ENSG0000015493044
ACSS3 / Q9H6R3 / acyl-CoA synthetase short chain family member 3ENSG0000011105832
ACSM3 / Q53FZ2 / acyl-CoA synthetase medium chain family member 3ENSG0000000518722
ACSM5 / Q6NUN0 / acyl-CoA synthetase medium chain family member 5ENSG0000018354922
ACSM1 / Q08AH1 / acyl-CoA synthetase medium chain family member 1ENSG0000016674321
ACSM4 / P0C7M7 / acyl-CoA synthetase medium chain family member 4ENSG0000021500921
ACSM2B / Q68CK6 / acyl-CoA synthetase medium chain family member 2BENSG0000006681320
ACSM2A / Q08AH3 / acyl-CoA synthetase medium chain family member 2AENSG0000018374720
ACSM6 / Q6P461 / acyl-CoA synthetase medium chain family member 6ENSG0000017312414


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR011904  Acetate-CoA ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain
 IPR032387  Acetyl-coenzyme A synthetase, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006069 ethanol oxidation TAS
 biological_processGO:0006085 acetyl-CoA biosynthetic process IEA
 biological_processGO:0007005 mitochondrion organization TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008610 lipid biosynthetic process IMP
 biological_processGO:0019413 acetate biosynthetic process IEA
 biological_processGO:0019427 acetyl-CoA biosynthetic process from acetate IEA
 biological_processGO:0019542 propionate biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003987 acetate-CoA ligase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016208 AMP binding IC
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000142082 SIRT3 / Q9NTG7 / sirtuin 3  / reaction






 

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