ENSMUSG00000027605


Mus musculus

Features
Gene ID: ENSMUSG00000027605
  
Biological name :Acss2
  
Synonyms : Acetyl-coenzyme A synthetase, cytoplasmic / Acss2 / Q9QXG4
  
Possible biological names infered from orthology : acyl-CoA synthetase short chain family member 2 / Q9NR19
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 155517948
Gene end: 155585724
  
Corresponding Affymetrix probe sets: 10477649 (MoGene1.0st)   1422478_a_at (Mouse Genome 430 2.0 Array)   1422479_at (Mouse Genome 430 2.0 Array)   1446542_at (Mouse Genome 430 2.0 Array)   1457460_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122545
Ensembl peptide - ENSMUSP00000068776
Ensembl peptide - ENSMUSP00000099431
Ensembl peptide - ENSMUSP00000116501
Ensembl peptide - ENSMUSP00000029135
NCBI entrez gene - 60525     See in Manteia.
MGI - MGI:1890410
RefSeq - XM_017319156
RefSeq - NM_019811
RefSeq - XM_006499973
RefSeq - XM_006499974
RefSeq - XM_006499975
RefSeq Peptide - NP_062785
swissprot - Q9QXG4
swissprot - D6RHA7
swissprot - F7CU63
swissprot - A2AQN5
swissprot - A2AQN4
Ensembl - ENSMUSG00000027605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acss2ENSDARG00000037781Danio rerio
 ACSS2ENSGALG00000003362Gallus gallus
 ACSS2ENSG00000131069Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acss1 / Q99NB1 / Acetyl-coenzyme A synthetase 2-like, mitochondrial / Q9NUB1* / acyl-CoA synthetase short chain family member 1*ENSMUSG0000002745245
Acss3 / Q14DH7 / Acyl-CoA synthetase short-chain family member 3, mitochondrial / Q9H6R3* / acyl-CoA synthetase short chain family member 3*ENSMUSG0000003594832
Acsm3 / Q3UNX5 / Acyl-coenzyme A synthetase ACSM3, mitochondrial / Q53FZ2* / acyl-CoA synthetase medium chain family member 3*ENSMUSG0000003093524
Acsm4 / Q80W40 / Acyl-coenzyme A synthetase ACSM4, mitochondrial / P0C7M7* / acyl-CoA synthetase medium chain family member 4*ENSMUSG0000004702622
Acsm5 / Q8BGA8 / Acyl-coenzyme A synthetase ACSM5, mitochondrial / Q6NUN0* / acyl-CoA synthetase medium chain family member 5*ENSMUSG0000003097222
Acsm1 / Q91VA0 / Acyl-coenzyme A synthetase ACSM1, mitochondrial / Q08AH1* / acyl-CoA synthetase medium chain family member 1*ENSMUSG0000003353322
Acsm2 / Q8K0L3 / Acyl-coenzyme A synthetase ACSM2, mitochondrial / ACSM2B* / Q68CK6* / ACSM2A* / Q08AH3* / acyl-CoA synthetase medium chain family member 2B* / acyl-CoA synthetase medium c...ENSMUSG0000003094520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR011904  Acetate-CoA ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain
 IPR032387  Acetyl-coenzyme A synthetase, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006085 acetyl-CoA biosynthetic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008610 lipid biosynthetic process IEA
 biological_processGO:0019413 acetate biosynthetic process IEA
 biological_processGO:0019427 acetyl-CoA biosynthetic process from acetate IEA
 biological_processGO:0019542 propionate biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003987 acetate-CoA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016208 AMP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025486 Sirt3 / Q8R104 / sirtuin 3 / Q9NTG7*  / reaction






 

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