Manteia

ENSMUSG00000030945

Mus musculus

Features

Gene ID:	ENSMUSG00000030945

Biological name :	Acsm2

Synonyms :	Acsm2 / Acyl-coenzyme A synthetase ACSM2, mitochondrial / Q8K0L3

Possible biological names infered from orthology :	ACSM2A / ACSM2B / acyl-CoA synthetase medium chain family member 2A / acyl-CoA synthetase medium chain family member 2B / Q08AH3 / Q68CK6

Species:	Mus musculus

Chr. number:	7
Strand:	1
Band:	F2
Gene start:	119554340
Gene end:	119600690

Corresponding Affymetrix probe sets:	10556718 (MoGene1.0st) 1427215_at (Mouse Genome 430 2.0 Array) 1427223_a_at (Mouse Genome 430 2.0 Array) 1427224_at (Mouse Genome 430 2.0 Array) 1456190_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000118276 Ensembl peptide - ENSMUSP00000146746 Ensembl peptide - ENSMUSP00000146400 Ensembl peptide - ENSMUSP00000126670 Ensembl peptide - ENSMUSP00000081697 Ensembl peptide - ENSMUSP00000095690 Ensembl peptide - ENSMUSP00000115048 Ensembl peptide - ENSMUSP00000118174 NCBI entrez gene - 233799 See in Manteia. MGI - MGI:2385289 RefSeq - NM_146197 RefSeq - NM_001177977 RefSeq - NM_001177978 RefSeq Peptide - NP_001171449 RefSeq Peptide - NP_001171448 RefSeq Peptide - NP_666309 swissprot - Q8K0L3 swissprot - A0A140LIB0 swissprot - A0A140LHG2 swissprot - F6V4U2 swissprot - F6XLJ8 swissprot - D3YXB1 Ensembl - ENSMUSG00000030945

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Acsm4 / Q80W40 / Acyl-coenzyme A synthetase ACSM4, mitochondrial / P0C7M7* / acyl-CoA synthetase medium chain family member 4*	ENSMUSG00000047026	54
Acsm1 / Q91VA0 / Acyl-coenzyme A synthetase ACSM1, mitochondrial / Q08AH1* / acyl-CoA synthetase medium chain family member 1*	ENSMUSG00000033533	50
Acsm3 / Q3UNX5 / Acyl-coenzyme A synthetase ACSM3, mitochondrial / Q53FZ2* / acyl-CoA synthetase medium chain family member 3*	ENSMUSG00000030935	50
Acsm5 / Q8BGA8 / Acyl-coenzyme A synthetase ACSM5, mitochondrial / Q6NUN0* / acyl-CoA synthetase medium chain family member 5*	ENSMUSG00000030972	50
Acss1 / Q99NB1 / Acetyl-coenzyme A synthetase 2-like, mitochondrial / Q9NUB1* / acyl-CoA synthetase short chain family member 1*	ENSMUSG00000027452	25
Acss3 / Q14DH7 / Acyl-CoA synthetase short-chain family member 3, mitochondrial / Q9H6R3* / acyl-CoA synthetase short chain family member 3*	ENSMUSG00000035948	23
Acss2 / Q9QXG4 / Acetyl-coenzyme A synthetase, cytoplasmic / Q9NR19* / acyl-CoA synthetase short chain family member 2*	ENSMUSG00000027605	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR000873	AMP-dependent synthetase/ligase
IPR020845	AMP-binding, conserved site
IPR025110	AMP-binding enzyme, C-terminal domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006629	lipid metabolic process	IEA
biological_process	GO:0006631	fatty acid metabolic process	IEA
biological_process	GO:0006633	fatty acid biosynthetic process	IBA
biological_process	GO:0006637	acyl-CoA metabolic process	IBA
biological_process	GO:0008152	metabolic process	IEA
biological_process	GO:0036112	medium-chain fatty-acyl-CoA metabolic process	ISO
cellular_component	GO:0005739	mitochondrion	IDA
cellular_component	GO:0005759	mitochondrial matrix	IBA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003824	catalytic activity	IEA
molecular_function	GO:0003996	acyl-CoA ligase activity	IBA
molecular_function	GO:0004321	fatty-acyl-CoA synthase activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0015645	fatty acid ligase activity	IBA
molecular_function	GO:0016874	ligase activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0047760	butyrate-CoA ligase activity	ISO

Pathways (from Reactome)

Pathway description

Conjugation of salicylate with glycine

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001510	abnormal coat appearance	"coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Abcc2^{tm2b(KOMP)Wtsi}/Abcc2^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Abcc2^{tm2b(KOMP)Wtsi}/H
MP:0003020	decreased circulating chloride level	"reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Abcc2^{tm2b(KOMP)Wtsi}/Abcc2^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Abcc2^{tm2b(KOMP)Wtsi}/H
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Abcc2^{tm2b(KOMP)Wtsi}/Abcc2^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Abcc2^{tm2b(KOMP)Wtsi}/H

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr