ENSG00000166887


Homo sapiens

Features
Gene ID: ENSG00000166887
  
Biological name :VPS39
  
Synonyms : Q96JC1 / VPS39 / VPS39, HOPS complex subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q15.1
Gene start: 42158701
Gene end: 42208316
  
Corresponding Affymetrix probe sets: 212156_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457325
Ensembl peptide - ENSP00000326534
Ensembl peptide - ENSP00000335193
NCBI entrez gene - 23339     See in Manteia.
OMIM - 612188
RefSeq - XM_017022039
RefSeq - XM_011521403
RefSeq - XM_011521404
RefSeq - XM_017022036
RefSeq - XM_017022037
RefSeq - XM_017022038
RefSeq - NM_001301138
RefSeq - NM_015289
RefSeq Peptide - NP_001288067
RefSeq Peptide - NP_056104
swissprot - H3BTU0
swissprot - Q96JC1
swissprot - A0A024R9L9
Ensembl - ENSG00000166887
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps39ENSDARG00000074471Danio rerio
 VPS39ENSGALG00000008991Gallus gallus
 Vps39ENSMUSG00000027291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WUH2 / TGFBRAP1 / transforming growth factor beta receptor associated protein 1ENSG0000013596623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR001180  Citron homology (CNH) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR019452  Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1
 IPR019453  Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2
 IPR032914  Vam6/VPS39/TRAP1 family
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034058 endosomal vesicle fusion IDA
 biological_processGO:1902774 late endosome to lysosome transport IDA
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0031902 late endosome membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr