ENSG00000135966


Homo sapiens

Features
Gene ID: ENSG00000135966
  
Biological name :TGFBRAP1
  
Synonyms : Q8WUH2 / TGFBRAP1 / transforming growth factor beta receptor associated protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q12.2
Gene start: 105264391
Gene end: 105330034
  
Corresponding Affymetrix probe sets: 205210_at (Human Genome U133 Plus 2.0 Array)   221235_s_at (Human Genome U133 Plus 2.0 Array)   225653_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258449
Ensembl peptide - ENSP00000377027
Ensembl peptide - ENSP00000471434
NCBI entrez gene - 9392     See in Manteia.
OMIM - 606237
RefSeq - XM_017005339
RefSeq - NM_001142621
RefSeq - NM_004257
RefSeq - XM_011512193
RefSeq Peptide - NP_001136093
RefSeq Peptide - NP_004248
swissprot - Q8WUH2
Ensembl - ENSG00000135966
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tgfbrap1ENSDARG00000061508Danio rerio
 TGFBRAP1ENSGALG00000016795Gallus gallus
 Q3UR70ENSMUSG00000070939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VPS39 / Q96JC1 / VPS39, HOPS complex subunitENSG0000016688724


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR001180  Citron homology (CNH) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR019452  Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1
 IPR019453  Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2
 IPR032914  Vam6/VPS39/TRAP1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034058 endosomal vesicle fusion IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0033263 CORVET complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046332 SMAD binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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