ENSG00000167720


Homo sapiens

Features
Gene ID: ENSG00000167720
  
Biological name :SRR
  
Synonyms : Q9GZT4 / serine racemase / SRR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.3
Gene start: 2303383
Gene end: 2325260
  
Corresponding Affymetrix probe sets: 219204_s_at (Human Genome U133 Plus 2.0 Array)   219205_at (Human Genome U133 Plus 2.0 Array)   222844_s_at (Human Genome U133 Plus 2.0 Array)   235677_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476682
Ensembl peptide - ENSP00000461482
Ensembl peptide - ENSP00000461589
Ensembl peptide - ENSP00000339435
Ensembl peptide - ENSP00000458814
Ensembl peptide - ENSP00000460581
Ensembl peptide - ENSP00000461125
Ensembl peptide - ENSP00000461343
NCBI entrez gene - 63826     See in Manteia.
OMIM - 606477
RefSeq - XM_011523974
RefSeq - NM_001304803
RefSeq - NM_021947
RefSeq - XM_006721565
RefSeq - XM_006721566
RefSeq Peptide - NP_001291732
RefSeq Peptide - NP_068766
swissprot - Q9GZT4
swissprot - I3L4B4
swissprot - I3L4L3
swissprot - I3L4W4
swissprot - I3L3N0
swissprot - V9GYE8
swissprot - Q3ZK31
Ensembl - ENSG00000167720
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-263o4.3ENSDARG00000096207Danio rerio
 si:ch73-263o4.4ENSDARG00000096045Danio rerio
 SRRENSGALG00000003155Gallus gallus
 SrrENSMUSG00000001323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000634  Serine/threonine dehydratase, pyridoxal-phosphate-binding site
 IPR001926  Pyridoxal-phosphate dependent enzyme
 IPR036052  Tryptophan synthase beta subunit-like PLP-dependent enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0006563 L-serine metabolic process IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009069 serine family amino acid metabolic process IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0032496 response to lipopolysaccharide IEP
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042866 pyruvate biosynthetic process IDA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0070178 D-serine metabolic process IEA
 biological_processGO:0070179 D-serine biosynthetic process IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003941 L-serine ammonia-lyase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0008721 D-serine ammonia-lyase activity IEA
 molecular_functionGO:0016594 glycine binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0018114 threonine racemase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IPI
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0030378 serine racemase activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167720 SRR / Q9GZT4 / serine racemase  / complex






 

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