ENSG00000168090


Homo sapiens

Features
Gene ID: ENSG00000168090
  
Biological name :COPS6
  
Synonyms : COP9 signalosome subunit 6 / COPS6 / Q7L5N1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 100088954
Gene end: 100092200
  
Corresponding Affymetrix probe sets: 201405_s_at (Human Genome U133 Plus 2.0 Array)   213504_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304102
Ensembl peptide - ENSP00000413702
Ensembl peptide - ENSP00000400617
Ensembl peptide - ENSP00000388865
NCBI entrez gene - 10980     See in Manteia.
OMIM - 614729
RefSeq - NM_006833
RefSeq Peptide - NP_006824
swissprot - Q7L5N1
swissprot - H7C3T0
swissprot - C9JQK5
swissprot - E7EM64
Ensembl - ENSG00000168090
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cops6ENSMUSG00000019494Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EIF3F / O00303 / eukaryotic translation initiation factor 3 subunit FENSG0000017539023
PSMD7 / P51665 / proteasome 26S subunit, non-ATPase 7ENSG0000010303521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR024969  Rpn11/EIF3F, C-terminal
 IPR033859  COP9 signalosome subunit 6
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000338 protein deneddylation IEA
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition TAS
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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