ENSG00000168806


Homo sapiens

Features
Gene ID: ENSG00000168806
  
Biological name :LCMT2
  
Synonyms : LCMT2 / leucine carboxyl methyltransferase 2 / O60294
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q15.3
Gene start: 43323649
Gene end: 43330605
  
Corresponding Affymetrix probe sets: 204012_s_at (Human Genome U133 Plus 2.0 Array)   204013_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307214
Ensembl peptide - ENSP00000457403
NCBI entrez gene - 9836     See in Manteia.
OMIM - 611246
RefSeq - NM_014793
RefSeq Peptide - NP_055608
swissprot - O60294
swissprot - H3BU01
Ensembl - ENSG00000168806
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lcmt2ENSDARG00000000747Danio rerio
 LCMT2ENSGALG00000017333Gallus gallus
 Lcmt2ENSMUSG00000074890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LCMT1 / Q9UIC8 / leucine carboxyl methyltransferase 1ENSG0000020562916


Protein motifs (from Interpro)
Interpro ID Name
 IPR007213  Methyltransferase Ppm1/Ppm2/Tcmp
 IPR015915  Kelch-type beta propeller
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification TAS
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IBA
 biological_processGO:0031591 wybutosine biosynthetic process IBA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008175 tRNA methyltransferase activity TAS
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of wybutosine at G37 of tRNA(Phe)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr