ENSG00000169727


Homo sapiens

Features
Gene ID: ENSG00000169727
  
Biological name :GPS1
  
Synonyms : G protein pathway suppressor 1 / GPS1 / Q13098
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.3
Gene start: 82050691
Gene end: 82057470
  
Corresponding Affymetrix probe sets: 217782_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464571
Ensembl peptide - ENSP00000464530
Ensembl peptide - ENSP00000464575
Ensembl peptide - ENSP00000485641
Ensembl peptide - ENSP00000485330
Ensembl peptide - ENSP00000485035
Ensembl peptide - ENSP00000302873
Ensembl peptide - ENSP00000313569
Ensembl peptide - ENSP00000376167
Ensembl peptide - ENSP00000461965
Ensembl peptide - ENSP00000462029
Ensembl peptide - ENSP00000462213
Ensembl peptide - ENSP00000462265
Ensembl peptide - ENSP00000462297
Ensembl peptide - ENSP00000462391
Ensembl peptide - ENSP00000462705
Ensembl peptide - ENSP00000462896
Ensembl peptide - ENSP00000463381
Ensembl peptide - ENSP00000463514
Ensembl peptide - ENSP00000463690
Ensembl peptide - ENSP00000463823
Ensembl peptide - ENSP00000463937
NCBI entrez gene - 2873     See in Manteia.
OMIM - 601934
RefSeq - XM_017024535
RefSeq - NM_001321089
RefSeq - NM_001321090
RefSeq - NM_001321091
RefSeq - NM_001321092
RefSeq - NM_001321093
RefSeq - NM_004127
RefSeq - NM_212492
RefSeq - XM_005256350
RefSeq - XM_005256353
RefSeq - XM_005256359
RefSeq - XM_005256360
RefSeq - XM_011523569
RefSeq - XM_011523570
RefSeq - XM_017024524
RefSeq - XM_017024525
RefSeq - XM_017024526
RefSeq - XM_017024527
RefSeq - XM_017024528
RefSeq - XM_017024529
RefSeq - XM_017024530
RefSeq - XM_017024531
RefSeq - XM_017024532
RefSeq - XM_017024533
RefSeq - XM_017024534
RefSeq Peptide - NP_001308019
RefSeq Peptide - NP_001308020
RefSeq Peptide - NP_001308021
RefSeq Peptide - NP_001308022
RefSeq Peptide - NP_001317468
RefSeq Peptide - NP_001317470
RefSeq Peptide - NP_004118
RefSeq Peptide - NP_997657
RefSeq Peptide - NP_001308018
swissprot - J3KSA5
swissprot - J3KSY1
swissprot - J3KTB0
swissprot - J3QL53
swissprot - J3QLE8
swissprot - J3QLT0
swissprot - J3QQP2
swissprot - J3QQX0
swissprot - J3QS84
swissprot - J3QS88
swissprot - A0A096LP07
swissprot - Q13098
swissprot - C9JFE4
swissprot - A8K070
swissprot - A0A096LPJ3
swissprot - J3KRE8
swissprot - J3KRJ4
swissprot - J3KRY5
Ensembl - ENSG00000169727
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gps1ENSDARG00000040650Danio rerio
 GPS1ENSGALG00000002827Gallus gallus
 Gps1ENSMUSG00000025156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PSMD6 / Q15008 / proteasome 26S subunit, non-ATPase 6ENSG0000016363616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR019585  26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1
 IPR033008  COP9 signalosome complex subunit 1
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity TAS
 biological_processGO:0000338 protein deneddylation IEA
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition TAS
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008180 COP9 signalosome IEA
 molecular_functionGO:0005095 GTPase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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