ENSMUSG00000025156


Mus musculus

Features
Gene ID: ENSMUSG00000025156
  
Biological name :Gps1
  
Synonyms : G protein pathway suppressor 1 / Gps1
  
Possible biological names infered from orthology : Q13098
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 120784272
Gene end: 120789102
  
Corresponding Affymetrix probe sets: 10383485 (MoGene1.0st)   10436446 (MoGene1.0st)   10338117 (MoGene1.0st)   10338988 (MoGene1.0st)   10339346 (MoGene1.0st)   10339411 (MoGene1.0st)   10340203 (MoGene1.0st)   10340729 (MoGene1.0st)   10340737 (MoGene1.0st)   10340872 (MoGene1.0st)   10341701 (MoGene1.0st)   10342131 (MoGene1.0st)   10342504 (MoGene1.0st)   10342522 (MoGene1.0st)   10342698 (MoGene1.0st)   10343248 (MoGene1.0st)   10339624 (MoGene1.0st)   10342155 (MoGene1.0st)   10343093 (MoGene1.0st)   1415699_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147152
Ensembl peptide - ENSMUSP00000112007
Ensembl peptide - ENSMUSP00000123512
Ensembl peptide - ENSMUSP00000133855
Ensembl peptide - ENSMUSP00000097711
NCBI entrez gene - 209318     See in Manteia.
MGI - MGI:2384801
RefSeq - XM_017314412
RefSeq - NM_001177874
RefSeq - NM_001346709
RefSeq - NM_145370
RefSeq - XM_006532744
RefSeq - XM_006532745
RefSeq - XM_017314409
RefSeq - XM_017314410
RefSeq - XM_017314411
RefSeq Peptide - NP_663345
RefSeq Peptide - NP_001171345
RefSeq Peptide - NP_001333638
swissprot - D6RCV3
swissprot - A0A140LJB7
swissprot - Q3MIA8
swissprot - G3UXW9
swissprot - B1ATU4
Ensembl - ENSMUSG00000025156
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gps1ENSDARG00000040650Danio rerio
 GPS1ENSGALG00000002827Gallus gallus
 GPS1ENSG00000169727Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Psmd6 / Q99JI4 / 26S proteasome non-ATPase regulatory subunit 6 / Q15008* / proteasome 26S subunit, non-ATPase 6*ENSMUSG0000002173716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR019585  26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1
 IPR033008  COP9 signalosome complex subunit 1
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000338 protein deneddylation IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0000288 abnormal pericardium morphology "malformation of the fibroserous membrane covering the heart and beginning of the great vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:54408]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0004848 abnormal liver size "anomaly in the average size of the liver " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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