ENSG00000170367


Homo sapiens

Features
Gene ID: ENSG00000170367
  
Biological name :CST5
  
Synonyms : CST5 / cystatin D / P28325
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p11.21
Gene start: 23875935
Gene end: 23879750
  
Corresponding Affymetrix probe sets: 207925_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307132
NCBI entrez gene - 1473     See in Manteia.
OMIM - 123858
RefSeq - NM_001900
RefSeq Peptide - NP_001891
swissprot - P28325
Ensembl - ENSG00000170367
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cst3ENSDARG00000007795Danio rerio
 zgc:163030ENSDARG00000069192Danio rerio
 CST3ENSGALG00000028520Gallus gallus
 Cst10ENSMUSG00000033156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CST2 / P09228 / cystatin SAENSG0000017036956
CST1 / P01037 / cystatin SNENSG0000017037354
CST4 / P01036 / cystatin SENSG0000010144154
CST3 / P01034 / cystatin CENSG0000010143951
CST7 / O76096 / cystatin FENSG0000007798425
CST6 / Q15828 / cystatin E/MENSG0000017531525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000010  Cystatin domain
 IPR018073  Proteinase inhibitor I25, cystatin, conserved site
 IPR027214  Cystatin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:2000117 negative regulation of cysteine-type endopeptidase activity IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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