ENSG00000170373


Homo sapiens

Features
Gene ID: ENSG00000170373
  
Biological name :CST1
  
Synonyms : CST1 / cystatin SN / P01037
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p11.21
Gene start: 23747553
Gene end: 23751268
  
Corresponding Affymetrix probe sets: 206224_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381439
Ensembl peptide - ENSP00000305731
NCBI entrez gene - 1469     See in Manteia.
OMIM - 123855
RefSeq - NM_001898
RefSeq Peptide - NP_001889
swissprot - P01037
Ensembl - ENSG00000170373
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cst3ENSDARG00000007795Danio rerio
 zgc:163030ENSDARG00000069192Danio rerio
 CST3ENSGALG00000028520Gallus gallus
 Cst10ENSMUSG00000033156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CST4 / P01036 / cystatin SENSG0000010144187
CST2 / P09228 / cystatin SAENSG0000017036986
CST3 / P01034 / cystatin CENSG0000010143957
CST5 / P28325 / cystatin DENSG0000017036755
CST6 / Q15828 / cystatin E/MENSG0000017531533
CST7 / O76096 / cystatin FENSG0000007798429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000010  Cystatin domain
 IPR018073  Proteinase inhibitor I25, cystatin, conserved site
 IPR027214  Cystatin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste IDA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:2000117 negative regulation of cysteine-type endopeptidase activity IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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