ENSDARG00000007795


Danio rerio

Features
Gene ID: ENSDARG00000007795
  
Biological name :cst3
  
Synonyms : cst3 / cystatin C (amyloid angiopathy and cerebral hemorrhage)
  
Possible biological names infered from orthology : CST1 / Cst10 / CST2 / CST4 / CST5 / CST6 / Cystatin 10 / cystatin C / cystatin D / cystatin E/M / cystatin S / cystatin SA / cystatin SN / P01034 / P01036 / P01037 / P09228 / P21460 / P28325 / Q15828 / Q9JM84
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 33675556
Gene end: 33683913
  
Corresponding Affymetrix probe sets: Dr.2902.1.S1_at (Zebrafish Array)   NM_001031673_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000065434
Ensembl peptide - ENSDARP00000113296
NCBI entrez gene - 791878     See in Manteia.
RefSeq - NM_001031673
RefSeq Peptide - NP_001026843
swissprot - B8A4D0
swissprot - B8A4C9
ZFIN ID - ZDB-GENE-030131-373
Ensembl - ENSDARG00000007795
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CST3ENSGALG00000028520Gallus gallus
 CST1ENSG00000170373Homo sapiens
 CST2ENSG00000170369Homo sapiens
 CST3ENSG00000101439Homo sapiens
 CST4ENSG00000101441Homo sapiens
 CST5ENSG00000170367Homo sapiens
 CST6ENSG00000175315Homo sapiens
 Cst10ENSMUSG00000033156Mus musculus
 Cst3ENSMUSG00000027447Mus musculus
 Cst6ENSMUSG00000024846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:163030 / CST3* / CST4* / CST5* / CST6* / CST1* / CST2* / Cst10* / P01036* / P01034* / P01037* / P09228* / P21460* / P28325* / Q15828* / Q9JM84* / cystatin C* / cystatin D* / cystatin S*...ENSDARG0000006919268


Protein motifs (from Interpro)
Interpro ID Name
 IPR000010  Cystatin domain
 IPR018073  Proteinase inhibitor I25, cystatin, conserved site
 IPR027214  Cystatin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:2000117 negative regulation of cysteine-type endopeptidase activity IBA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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