ENSG00000170471


Homo sapiens

Features
Gene ID: ENSG00000170471
  
Biological name :RALGAPB
  
Synonyms : Q86X10 / RALGAPB / Ral GTPase activating protein non-catalytic beta subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.23
Gene start: 38472816
Gene end: 38578861
  
Corresponding Affymetrix probe sets: 221736_at (Human Genome U133 Plus 2.0 Array)   221738_at (Human Genome U133 Plus 2.0 Array)   224678_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416646
Ensembl peptide - ENSP00000487816
Ensembl peptide - ENSP00000262879
Ensembl peptide - ENSP00000380233
Ensembl peptide - ENSP00000380235
NCBI entrez gene - 57148     See in Manteia.
RefSeq - XM_017027970
RefSeq - XM_005260464
RefSeq - XM_005260465
RefSeq - XM_017027966
RefSeq - XM_017027967
RefSeq - XM_017027968
RefSeq - XM_017027969
RefSeq - NM_001282917
RefSeq - NM_001282918
RefSeq - NM_020336
RefSeq - XM_005260462
RefSeq - XM_005260463
RefSeq Peptide - NP_065069
RefSeq Peptide - NP_001269846
RefSeq Peptide - NP_001269847
swissprot - A2A2F0
swissprot - Q86X10
swissprot - A0A0J9YW54
Ensembl - ENSG00000170471
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ralgapbENSDARG00000088899Danio rerio
 RALGAPBENSGALG00000001420Gallus gallus
 RalgapbENSMUSG00000027652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR011989  Armadillo-like helical
 IPR035974  Rap/Ran-GAP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 biological_processGO:0090630 activation of GTPase activity ISS
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISS


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000188559 Q2PPJ7 / RALGAPA2 / Ral GTPase activating protein catalytic alpha subunit 2  / complex
 ENSG00000105221 AKT2 / P31751 / AKT serine/threonine kinase 2  / reaction






 

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contact: otassy@igbmc.fr