ENSG00000170961


Homo sapiens

Features
Gene ID: ENSG00000170961
  
Biological name :HAS2
  
Synonyms : HAS2 / hyaluronan synthase 2 / Q92819
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.13
Gene start: 121612116
Gene end: 121641390
  
Corresponding Affymetrix probe sets: 206432_at (Human Genome U133 Plus 2.0 Array)   230372_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306991
NCBI entrez gene - 3037     See in Manteia.
OMIM - 601636
RefSeq - NM_005328
RefSeq Peptide - NP_005319
swissprot - Q92819
Ensembl - ENSG00000170961
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 has2ENSDARG00000036987Danio rerio
 HAS2ENSGALG00000029596Gallus gallus
 Has2ENSMUSG00000022367Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HAS3 / O00219 / hyaluronan synthase 3ENSG0000010304470
HAS1 / Q92839 / hyaluronan synthase 1ENSG0000010550953


Protein motifs (from Interpro)
Interpro ID Name
 IPR001173  Glycosyltransferase 2-like
 IPR028371  Hyaluronan synthase 2
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010838 positive regulation of keratinocyte proliferation IEA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0030212 hyaluronan metabolic process IEA
 biological_processGO:0030213 hyaluronan biosynthetic process IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0035810 positive regulation of urine volume IEA
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IDA
 biological_processGO:0036302 atrioventricular canal development IEA
 biological_processGO:0044849 estrous cycle IEA
 biological_processGO:0045226 extracellular polysaccharide biosynthetic process IEA
 biological_processGO:0051549 positive regulation of keratinocyte migration IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0070295 renal water absorption IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEP
 biological_processGO:0071356 cellular response to tumor necrosis factor IEP
 biological_processGO:0071498 cellular response to fluid shear stress IEP
 biological_processGO:0085029 extracellular matrix assembly IEA
 biological_processGO:0090500 endocardial cushion to mesenchymal transition IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 biological_processGO:1900127 positive regulation of hyaluronan biosynthetic process IEA
 biological_processGO:1900625 positive regulation of monocyte aggregation IMP
 biological_processGO:1901201 regulation of extracellular matrix assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0050501 hyaluronan synthase activity IMP


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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