ENSG00000172497


Homo sapiens

Features
Gene ID: ENSG00000172497
  
Biological name :ACOT12
  
Synonyms : ACOT12 / acyl-CoA thioesterase 12 / Q8WYK0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q14.1
Gene start: 81330005
Gene end: 81394179
  
Corresponding Affymetrix probe sets: 238160_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303246
Ensembl peptide - ENSP00000421628
NCBI entrez gene - 134526     See in Manteia.
OMIM - 614315
RefSeq - XM_017009047
RefSeq - NM_130767
RefSeq - XM_017009045
RefSeq - XM_017009046
RefSeq - XM_006714531
RefSeq - XM_006714532
RefSeq Peptide - NP_570123
swissprot - Q8WYK0
Ensembl - ENSG00000172497
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACOT12ENSDARG00000054534Danio rerio
 ACOT12ENSGALG00000015616Gallus gallus
 Acot12ENSMUSG00000021620Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACOT11 / Q8WXI4 / acyl-CoA thioesterase 11ENSG0000016239046
ACOT7 / O00154 / acyl-CoA thioesterase 7ENSG0000009702114


Protein motifs (from Interpro)
Interpro ID Name
 IPR002913  START domain
 IPR006683  Thioesterase domain
 IPR023393  START-like domain superfamily
 IPR029069  HotDog domain superfamily
 IPR033120  Hotdog acyl-CoA thioesterase (ACOT)-type domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006084 acetyl-CoA metabolic process IBA
 biological_processGO:0006090 pyruvate metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0003986 acetyl-CoA hydrolase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172497 ACOT12 / Q8WYK0 / acyl-CoA thioesterase 12  / complex






 

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