ENSMUSG00000021620


Mus musculus

Features
Gene ID: ENSMUSG00000021620
  
Biological name :Acot12
  
Synonyms : Acot12 / acyl-CoA thioesterase 12 / Q9DBK0
  
Possible biological names infered from orthology : Q8WYK0
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: C3
Gene start: 91741512
Gene end: 91786148
  
Corresponding Affymetrix probe sets: 10406564 (MoGene1.0st)   1419395_at (Mouse Genome 430 2.0 Array)   1433064_at (Mouse Genome 430 2.0 Array)   1449457_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022120
NCBI entrez gene - 74156     See in Manteia.
MGI - MGI:1921406
RefSeq - XM_006517413
RefSeq - NM_028790
RefSeq Peptide - NP_083066
swissprot - Q9DBK0
swissprot - A2RSC2
Ensembl - ENSMUSG00000021620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACOT12ENSDARG00000054534Danio rerio
 ACOT12ENSGALG00000015616Gallus gallus
 ACOT12ENSG00000172497Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acot11 / Q8VHQ9 / acyl-CoA thioesterase 11 / Q8WXI4*ENSMUSG0000003485346
Acot7 / Q91V12 / Cytosolic acyl coenzyme A thioester hydrolase / O00154* / acyl-CoA thioesterase 7*ENSMUSG0000002893714


Protein motifs (from Interpro)
Interpro ID Name
 IPR002913  START domain
 IPR006683  Thioesterase domain
 IPR023393  START-like domain superfamily
 IPR029069  HotDog domain superfamily
 IPR033120  Hotdog acyl-CoA thioesterase (ACOT)-type domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006084 acetyl-CoA metabolic process IDA
 biological_processGO:0006090 pyruvate metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003986 acetyl-CoA hydrolase activity IEA
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021620 Acot12 / Q9DBK0 / acyl-CoA thioesterase 12 / Q8WYK0*  / complex






 

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