ENSG00000173611


Homo sapiens

Features
Gene ID: ENSG00000173611
  
Biological name :SCAI
  
Synonyms : Q8N9R8 / SCAI / suppressor of cancer cell invasion
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q33.3
Gene start: 124942608
Gene end: 125143506
  
Corresponding Affymetrix probe sets: 214997_at (Human Genome U133 Plus 2.0 Array)   228174_at (Human Genome U133 Plus 2.0 Array)   241754_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336756
Ensembl peptide - ENSP00000362650
Ensembl peptide - ENSP00000418148
Ensembl peptide - ENSP00000419358
Ensembl peptide - ENSP00000419576
NCBI entrez gene - 286205     See in Manteia.
RefSeq - NM_173690
RefSeq - NM_001144877
RefSeq Peptide - NP_001138349
RefSeq Peptide - NP_775961
swissprot - Q8N9R8
swissprot - H7C4U2
swissprot - H7C5A3
swissprot - Q3SXZ0
Ensembl - ENSG00000173611
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scaiENSDARG00000060865Danio rerio
 SCAIENSGALG00000001037Gallus gallus
 ScaiENSMUSG00000035236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016607  Protein SCAI, metazoan/viridiplantae
 IPR022709  Protein SCAI


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000112658 SRF / P11831 / serum response factor  / complex / reaction
 ENSG00000196588 MKL1 / Q969V6 / megakaryoblastic leukemia (translocation) 1  / reaction / complex






 

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