ENSG00000173673


Homo sapiens

Features
Gene ID: ENSG00000173673
  
Biological name :HES3
  
Synonyms : HES3 / hes family bHLH transcription factor 3 / Q5TGS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.31
Gene start: 6244192
Gene end: 6245578
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000367130
NCBI entrez gene - 390992     See in Manteia.
OMIM - 609971
RefSeq - NM_001024598
RefSeq Peptide - NP_001019769
swissprot - Q5TGS1
Ensembl - ENSG00000173673
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 her3ENSDARG00000076857Danio rerio
 Hes3ENSMUSG00000028946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021555 midbrain-hindbrain boundary morphogenesis IEA
 biological_processGO:0021557 oculomotor nerve development IEA
 biological_processGO:0021558 trochlear nerve development IEA
 biological_processGO:0021575 hindbrain morphogenesis IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0060164 regulation of timing of neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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