ENSG00000173726


Homo sapiens

Features
Gene ID: ENSG00000173726
  
Biological name :TOMM20
  
Synonyms : Q15388 / TOMM20 / translocase of outer mitochondrial membrane 20
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.3
Gene start: 235109336
Gene end: 235128936
  
Corresponding Affymetrix probe sets: 200662_s_at (Human Genome U133 Plus 2.0 Array)   212773_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355566
NCBI entrez gene - 9804     See in Manteia.
OMIM - 601848
RefSeq - NM_014765
RefSeq Peptide - NP_055580
swissprot - A0A024R3W2
swissprot - Q15388
Ensembl - ENSG00000173726
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DH66ENSDARG00000103566Danio rerio
 TOMM20ENSGALG00000035299Gallus gallus
 Q9DCC8ENSMUSG00000093904Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UXN7 / TOMM20L / translocase of outer mitochondrial membrane 20 likeENSG0000019686043


Protein motifs (from Interpro)
Interpro ID Name
 IPR002056  Protein import receptor MAS20
 IPR022422  Protein import receptor MAS20, metazoan
 IPR023392  Mitochondrial outer membrane translocase complex, Tom20 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006626 protein targeting to mitochondrion IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0014850 response to muscle activity IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016031 tRNA import into mitochondrion IBA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030150 protein import into mitochondrial matrix IBA
 biological_processGO:0070096 mitochondrial outer membrane translocase complex assembly IBA
 biological_processGO:1905242 response to 3,3",5-triiodo-L-thyronine IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005740 mitochondrial envelope IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005742 mitochondrial outer membrane translocase complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IBA
 cellular_componentGO:0044233 ER-mitochondrion membrane contact site IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IDA
 molecular_functionGO:0030943 mitochondrion targeting sequence binding IBA
 molecular_functionGO:0051082 unfolded protein binding IDA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Pink/Parkin Mediated Mitophagy
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000135093 USP30 / Q70CQ3 / ubiquitin specific peptidase 30  / complex






 

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