ENSG00000135093


Homo sapiens

Features
Gene ID: ENSG00000135093
  
Biological name :USP30
  
Synonyms : Q70CQ3 / ubiquitin specific peptidase 30 / USP30
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.11
Gene start: 109023089
Gene end: 109088026
  
Corresponding Affymetrix probe sets: 223602_at (Human Genome U133 Plus 2.0 Array)   227572_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443678
Ensembl peptide - ENSP00000440837
Ensembl peptide - ENSP00000473942
Ensembl peptide - ENSP00000474166
Ensembl peptide - ENSP00000257548
Ensembl peptide - ENSP00000376535
Ensembl peptide - ENSP00000438829
NCBI entrez gene - 84749     See in Manteia.
OMIM - 612492
RefSeq - XM_017020054
RefSeq - XM_005253962
RefSeq - XM_005253965
RefSeq - XM_006719653
RefSeq - XM_011538894
RefSeq - XM_017020048
RefSeq - XM_017020049
RefSeq - XM_017020050
RefSeq - XM_017020051
RefSeq - XM_017020052
RefSeq - XM_017020053
RefSeq - NM_001301175
RefSeq - NM_032663
RefSeq Peptide - NP_001288104
RefSeq Peptide - NP_116052
swissprot - F5H3L3
swissprot - F5H8D3
swissprot - S4R3D1
swissprot - A0A024RBM3
swissprot - Q70CQ3
swissprot - B3KUS5
swissprot - S4R354
swissprot - F5GXG2
Ensembl - ENSG00000135093
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp30ENSDARG00000056842Danio rerio
 USP30ENSGALG00000040265Gallus gallus
 Usp30ENSMUSG00000029592Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0008053 mitochondrial fusion ISS
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0035871 protein K11-linked deubiquitination IDA
 biological_processGO:0044313 protein K6-linked deubiquitination IDA
 biological_processGO:1901525 negative regulation of mitophagy IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IMP
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000173726 Q15388 / TOMM20 / translocase of outer mitochondrial membrane 20  / complex
 ENSG00000126858 RHOT1 / Q8IXI2 / ras homolog family member T1  / complex






 

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