ENSG00000173933


Homo sapiens

Features
Gene ID: ENSG00000173933
  
Biological name :RBM4
  
Synonyms : Q9BWF3 / RBM4 / RNA binding motif protein 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 66638617
Gene end: 66666682
  
Corresponding Affymetrix probe sets: 200997_at (Human Genome U133 Plus 2.0 Array)   213718_at (Human Genome U133 Plus 2.0 Array)   236157_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432020
Ensembl peptide - ENSP00000464349
Ensembl peptide - ENSP00000435821
Ensembl peptide - ENSP00000432150
Ensembl peptide - ENSP00000309166
Ensembl peptide - ENSP00000381680
Ensembl peptide - ENSP00000386561
Ensembl peptide - ENSP00000386894
Ensembl peptide - ENSP00000413497
Ensembl peptide - ENSP00000422301
Ensembl peptide - ENSP00000423572
NCBI entrez gene - 5936     See in Manteia.
OMIM - 602571
RefSeq - NM_001198843
RefSeq - NM_001198844
RefSeq - NM_002896
RefSeq Peptide - NP_001185773
RefSeq Peptide - NP_002887
RefSeq Peptide - NP_001185772
swissprot - Q9BWF3
swissprot - D6R9K7
swissprot - J3QRR5
swissprot - E9PB51
Ensembl - ENSG00000173933
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6IQ97ENSDARG00000036386Danio rerio
 rbm4.2ENSDARG00000055080Danio rerio
 rbm4.3ENSDARG00000022129Danio rerio
 Gm21992ENSMUSG00000096370Mus musculus
 Rbm4ENSMUSG00000094936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RBM4B / Q9BQ04 / RNA binding motif protein 4BENSG0000017391487
RBM14-RBM4 / RBM14-RBM4 readthroughENSG0000024864374
RBM14 / Q96PK6 / RNA binding motif protein 14ENSG0000023930632


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR001878  Zinc finger, CCHC-type
 IPR034897  RBM4, RNA recognition motif 1
 IPR034898  RBM4, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IDA
 biological_processGO:0002190 cap-independent translational initiation IDA
 biological_processGO:0002192 IRES-dependent translational initiation of linear mRNA IDA
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0017148 negative regulation of translation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0032055 negative regulation of translation in response to stress IDA
 biological_processGO:0035278 miRNA mediated inhibition of translation IDA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod ISS
 biological_processGO:0045947 negative regulation of translational initiation IDA
 biological_processGO:0046685 response to arsenic-containing substance IDA
 biological_processGO:0046822 regulation of nucleocytoplasmic transport IDA
 biological_processGO:0051149 positive regulation of muscle cell differentiation IDA
 biological_processGO:0097167 circadian regulation of translation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0010494 cytoplasmic stress granule IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0035198 miRNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0097157 pre-mRNA intronic binding IDA
 molecular_functionGO:0097158 pre-mRNA intronic pyrimidine-rich binding IDA


Pathways (from Reactome)
Pathway description
Circadian Clock


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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