ENSG00000174059


Homo sapiens

Features
Gene ID: ENSG00000174059
  
Biological name :CD34
  
Synonyms : CD34 / CD34 molecule / P28906
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.2
Gene start: 207880972
Gene end: 207911402
  
Corresponding Affymetrix probe sets: 209543_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310036
Ensembl peptide - ENSP00000348916
Ensembl peptide - ENSP00000356003
NCBI entrez gene - 947     See in Manteia.
OMIM - 142230
RefSeq - NM_001025109
RefSeq - NM_001773
RefSeq Peptide - NP_001020280
RefSeq Peptide - NP_001764
swissprot - P28906
swissprot - Q5JTA5
Ensembl - ENSG00000174059
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000001177Gallus gallus
 Cd34ENSMUSG00000016494Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008083  CD34 antigen
 IPR013836  CD34/Podocalyxin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001894 tissue homeostasis IDA
 biological_processGO:0001935 endothelial cell proliferation IDA
 biological_processGO:0003094 glomerular filtration IEP
 biological_processGO:0003158 endothelium development IEP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IBA
 biological_processGO:0007165 signal transduction IEP
 biological_processGO:0008217 regulation of blood pressure IDA
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0010628 positive regulation of gene expression IEP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030195 negative regulation of blood coagulation IDA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IDA
 biological_processGO:0032733 positive regulation of interleukin-10 production IDA
 biological_processGO:0035759 mesangial cell-matrix adhesion ISS
 biological_processGO:0038001 paracrine signaling IDA
 biological_processGO:0042482 positive regulation of odontogenesis IDA
 biological_processGO:0045019 negative regulation of nitric oxide biosynthetic process IDA
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0048870 cell motility IEP
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050900 leukocyte migration ISS
 biological_processGO:0060290 transdifferentiation IEP
 biological_processGO:0061042 vascular wound healing IEP
 biological_processGO:0071425 hematopoietic stem cell proliferation IMP
 biological_processGO:0071636 positive regulation of transforming growth factor beta production IDA
 biological_processGO:0071657 positive regulation of granulocyte colony-stimulating factor production IEP
 biological_processGO:0071971 extracellular exosome assembly IDA
 biological_processGO:0072011 glomerular endothelium development IEP
 biological_processGO:0072089 stem cell proliferation IEP
 biological_processGO:0072254 metanephric glomerular mesangial cell differentiation IEP
 biological_processGO:0098609 cell-cell adhesion IDA
 biological_processGO:1900035 negative regulation of cellular response to heat IDA
 biological_processGO:1900038 negative regulation of cellular response to hypoxia IDA
 biological_processGO:1900041 negative regulation of interleukin-2 secretion IMP
 biological_processGO:1900168 positive regulation of glial cell-derived neurotrophic factor secretion IDA
 biological_processGO:1901215 negative regulation of neuron death IDA
 biological_processGO:2001214 positive regulation of vasculogenesis IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IC
 cellular_componentGO:0009925 basal plasma membrane ISS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0036053 glomerular endothelium fenestra ISS
 cellular_componentGO:0045171 intercellular bridge IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0030246 carbohydrate binding IDA
 molecular_functionGO:0043199 sulfate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000188404 SELL / P14151 / selectin L  / reaction / complex






 

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