ENSG00000174243


Homo sapiens

Features
Gene ID: ENSG00000174243
  
Biological name :DDX23
  
Synonyms : DDX23 / DEAD-box helicase 23 / Q9BUQ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.12
Gene start: 48829764
Gene end: 48852842
  
Corresponding Affymetrix probe sets: 201440_at (Human Genome U133 Plus 2.0 Array)   40465_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310723
Ensembl peptide - ENSP00000448542
Ensembl peptide - ENSP00000449657
Ensembl peptide - ENSP00000449639
Ensembl peptide - ENSP00000446770
Ensembl peptide - ENSP00000446948
NCBI entrez gene - 9416     See in Manteia.
OMIM - 612172
RefSeq - NM_004818
RefSeq Peptide - NP_004809
swissprot - F8W1J5
swissprot - H0YI52
swissprot - H0YIL9
swissprot - A0A024R0Z3
swissprot - Q9BUQ8
swissprot - F8VVA2
Ensembl - ENSG00000174243
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx23ENSDARG00000021945Danio rerio
 Ddx23ENSMUSG00000003360Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000354 cis assembly of pre-catalytic spliceosome IC
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005682 U5 snRNP IDA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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