ENSG00000174444


Homo sapiens

Features
Gene ID: ENSG00000174444
  
Biological name :RPL4
  
Synonyms : P36578 / ribosomal protein L4 / RPL4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q22.31
Gene start: 66498015
Gene end: 66524532
  
Corresponding Affymetrix probe sets: 200089_s_at (Human Genome U133 Plus 2.0 Array)   201154_x_at (Human Genome U133 Plus 2.0 Array)   211710_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311430
Ensembl peptide - ENSP00000457268
Ensembl peptide - ENSP00000457442
Ensembl peptide - ENSP00000454281
NCBI entrez gene - 6124     See in Manteia.
OMIM - 180479
RefSeq - NM_000968
RefSeq Peptide - NP_000959
swissprot - P36578
swissprot - H3BM89
swissprot - H3BTP7
swissprot - H3BU31
Ensembl - ENSG00000174444
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl4ENSDARG00000041182Danio rerio
 RPL4ENSGALG00000007711Gallus gallus
 Rpl4ENSMUSG00000032399Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002136  Ribosomal protein L4/L1e
 IPR013000  Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site
 IPR023574  Ribosomal protein L4 domain superfamily
 IPR025755  60S ribosomal protein L4, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus HDA
 cellular_componentGO:0005737 cytoplasm HDA
 cellular_componentGO:0005791 rough endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr