ENSG00000174791


Homo sapiens

Features
Gene ID: ENSG00000174791
  
Biological name :RIN1
  
Synonyms : Q13671 / Ras and Rab interactor 1 / RIN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.2
Gene start: 66330242
Gene end: 66336840
  
Corresponding Affymetrix probe sets: 205211_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431185
Ensembl peptide - ENSP00000485911
Ensembl peptide - ENSP00000432798
Ensembl peptide - ENSP00000431550
Ensembl peptide - ENSP00000310406
NCBI entrez gene - 9610     See in Manteia.
OMIM - 605965
RefSeq - XM_011545399
RefSeq - XM_017018587
RefSeq - XM_011545401
RefSeq - XM_011545400
RefSeq - NM_004292
RefSeq Peptide - NP_004283
swissprot - Q13671
swissprot - E9PNR2
swissprot - H0YCG8
swissprot - A0A0S2Z4U0
swissprot - E9PMB8
Ensembl - ENSG00000174791
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rin1aENSDARG00000079095Danio rerio
 si:ch211-168d1.3ENSDARG00000070100Danio rerio
 Rin1ENSMUSG00000024883Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RIN2 / Q8WYP3 / Ras and Rab interactor 2ENSG0000013266932
RIN3 / Q8TB24 / Ras and Rab interactor 3ENSG0000010059927
RINL / Q6ZS11 / Ras and Rab interactor likeENSG0000018799417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000980  SH2 domain
 IPR003123  VPS9 domain
 IPR035867  Ras and Rab interactor 1, SH2 domain
 IPR036860  SH2 domain superfamily
 IPR037191  VPS9 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0031914 negative regulation of synaptic plasticity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017016 Ras GTPase binding IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity TAS


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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