ENSG00000175324


Homo sapiens

Features
Gene ID: ENSG00000175324
  
Biological name :LSM1
  
Synonyms : LSM1 / LSM1 homolog, mRNA degradation associated / O15116
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p11.23
Gene start: 38163321
Gene end: 38176730
  
Corresponding Affymetrix probe sets: 203534_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310596
Ensembl peptide - ENSP00000430021
Ensembl peptide - ENSP00000428307
NCBI entrez gene - 27257     See in Manteia.
OMIM - 607281
RefSeq - NM_014462
RefSeq Peptide - NP_055277
swissprot - E5RH18
swissprot - A0A0S2Z590
swissprot - E5RJ47
swissprot - O15116
Ensembl - ENSG00000175324
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsm1ENSDARG00000043177Danio rerio
 LSM1ENSGALG00000003245Gallus gallus
 Lsm1ENSMUSG00000037296Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR010920  LSM domain superfamily
 IPR034104  Sm-like protein Lsm1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0071044 histone mRNA catabolic process IMP
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005845 mRNA cap binding complex IBA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IEA
 cellular_componentGO:1990726 Lsm1-7-Pat1 complex IBA
 molecular_functionGO:0000339 RNA cap binding IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0036002 pre-mRNA binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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