ENSG00000175826


Homo sapiens

Features
Gene ID: ENSG00000175826
  
Biological name :CTDNEP1
  
Synonyms : CTDNEP1 / CTD nuclear envelope phosphatase 1 / O95476
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7243591
Gene end: 7252491
  
Corresponding Affymetrix probe sets: 200035_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461567
Ensembl peptide - ENSP00000461749
Ensembl peptide - ENSP00000321732
Ensembl peptide - ENSP00000458408
Ensembl peptide - ENSP00000458758
Ensembl peptide - ENSP00000458763
Ensembl peptide - ENSP00000459866
Ensembl peptide - ENSP00000460527
Ensembl peptide - ENSP00000460683
Ensembl peptide - ENSP00000461122
NCBI entrez gene - 23399     See in Manteia.
OMIM - 610684
RefSeq - NM_001143775
RefSeq - NM_015343
RefSeq Peptide - NP_001137247
RefSeq Peptide - NP_056158
swissprot - I3L4B2
swissprot - I3L4W0
swissprot - O95476
swissprot - I3L0X6
swissprot - I3L1D9
swissprot - I3L2R5
swissprot - I3L3K5
Ensembl - ENSG00000175826
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctdnep1bENSDARG00000035781Danio rerio
 Q5U395ENSDARG00000016519Danio rerio
 Q3TP92ENSMUSG00000018559Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTDSPL / O15194 / CTD small phosphatase likeENSG0000014467734
CTDSP1 / Q9GZU7 / CTD small phosphatase 1ENSG0000014457934
CTDSP2 / O14595 / CTD small phosphatase 2ENSG0000017521532


Protein motifs (from Interpro)
Interpro ID Name
 IPR004274  FCP1 homology domain
 IPR011948  Dullard phosphatase domain, eukaryotic
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0006998 nuclear envelope organization IDA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0007276 gamete generation IEA
 biological_processGO:0007498 mesoderm development IEA
 biological_processGO:0010867 positive regulation of triglyceride biosynthetic process IGI
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0034504 protein localization to nucleus IDA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005811 lipid droplet IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0071595 Nem1-Spo7 phosphatase complex IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Depolymerisation of the Nuclear Lamina


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134324 LPIN1 / Q14693 / lipin 1  / reaction
 ENSG00000205423 Q8N9A8 / CNEP1R1 / CTD nuclear envelope phosphatase 1 regulatory subunit 1  / complex






 

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