ENSG00000176945


Homo sapiens

Features
Gene ID: ENSG00000176945
  
Biological name :MUC20
  
Synonyms : MUC20 / mucin 20, cell surface associated / Q8N307
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q29
Gene start: 195720882
Gene end: 195741123
  
Corresponding Affymetrix probe sets: 226622_at (Human Genome U133 Plus 2.0 Array)   230043_at (Human Genome U133 Plus 2.0 Array)   231941_s_at (Human Genome U133 Plus 2.0 Array)   243774_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396774
Ensembl peptide - ENSP00000414350
Ensembl peptide - ENSP00000405629
Ensembl peptide - ENSP00000397774
Ensembl peptide - ENSP00000325431
NCBI entrez gene - 200958     See in Manteia.
OMIM - 610360
RefSeq - NM_001282506
RefSeq Peptide - NP_001269435
swissprot - Q8N307
swissprot - H7C102
swissprot - C9JJE7
swissprot - E9PH32
Ensembl - ENSG00000176945
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Muc20ENSMUSG00000035638Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IBA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0048012 hepatocyte growth factor receptor signaling pathway IEA
 biological_processGO:0051260 protein homooligomerization IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031528 microvillus membrane IEA
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Dectin-2 family
MET activates RAS signaling
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000019991 HGF / P14210 / hepatocyte growth factor  / reaction / complex
 ENSG00000105976 MET / P08581 / MET proto-oncogene, receptor tyrosine kinase  / complex / reaction






 

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