ENSG00000177963


Homo sapiens

Features
Gene ID: ENSG00000177963
  
Biological name :RIC8A
  
Synonyms : Q9NPQ8 / RIC8A / RIC8 guanine nucleotide exchange factor A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.5
Gene start: 207511
Gene end: 215113
  
Corresponding Affymetrix probe sets: 221647_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434833
Ensembl peptide - ENSP00000487470
Ensembl peptide - ENSP00000436610
Ensembl peptide - ENSP00000436192
Ensembl peptide - ENSP00000435167
Ensembl peptide - ENSP00000434896
Ensembl peptide - ENSP00000325941
Ensembl peptide - ENSP00000431163
Ensembl peptide - ENSP00000432008
Ensembl peptide - ENSP00000433009
Ensembl peptide - ENSP00000433968
NCBI entrez gene - 60626     See in Manteia.
OMIM - 609146
RefSeq - XM_005253052
RefSeq - XM_017018107
RefSeq - NM_021932
RefSeq - NM_001286134
RefSeq Peptide - NP_068751
RefSeq Peptide - NP_001273063
swissprot - Q9NPQ8
swissprot - H0YEN0
swissprot - E9PMP0
swissprot - E9PLE5
swissprot - E9PI04
swissprot - H0YC88
swissprot - H0YE35
swissprot - E9PSI0
Ensembl - ENSG00000177963
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ric8aENSDARG00000007247Danio rerio
 RIC8AENSGALG00000004191Gallus gallus
 Ric8aENSMUSG00000025485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RIC8B / Q9NVN3 / RIC8 guanine nucleotide exchange factor BENSG0000011178548


Protein motifs (from Interpro)
Interpro ID Name
 IPR008376  Synembryn
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR019318  Guanine nucleotide exchange factor, Ric8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001944 vasculature development IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0009416 response to light stimulus IEA
 biological_processGO:0042074 cell migration involved in gastrulation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070586 cell-cell adhesion involved in gastrulation IEA
 biological_processGO:0071711 basement membrane organization IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IBA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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