ENSG00000111785


Homo sapiens

Features
Gene ID: ENSG00000111785
  
Biological name :RIC8B
  
Synonyms : Q9NVN3 / RIC8B / RIC8 guanine nucleotide exchange factor B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.3
Gene start: 106774595
Gene end: 106889316
  
Corresponding Affymetrix probe sets: 219446_at (Human Genome U133 Plus 2.0 Array)   229637_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450396
Ensembl peptide - ENSP00000448743
Ensembl peptide - ENSP00000464118
Ensembl peptide - ENSP00000492690
Ensembl peptide - ENSP00000347662
Ensembl peptide - ENSP00000376582
Ensembl peptide - ENSP00000376583
Ensembl peptide - ENSP00000435301
Ensembl peptide - ENSP00000436359
Ensembl peptide - ENSP00000447701
Ensembl peptide - ENSP00000447801
NCBI entrez gene - 55188     See in Manteia.
OMIM - 609147
RefSeq - XM_017019549
RefSeq - NM_001330145
RefSeq - NM_001330146
RefSeq - NM_001351361
RefSeq - NM_001351366
RefSeq - NM_018157
RefSeq - XM_005268998
RefSeq - XM_011538526
RefSeq - XM_011538527
RefSeq - XM_011538528
RefSeq - XM_011538529
RefSeq - XM_017019548
RefSeq Peptide - NP_001317076
RefSeq Peptide - NP_001338290
RefSeq Peptide - NP_001338293
RefSeq Peptide - NP_001338295
RefSeq Peptide - NP_060627
RefSeq Peptide - NP_001317075
RefSeq Peptide - NP_001317074
swissprot - Q9NVN3
swissprot - A0A024RBG9
swissprot - B7WPL0
swissprot - F8VR30
swissprot - F8VSN5
swissprot - F8VY51
swissprot - H0YHS3
swissprot - J3QRA4
Ensembl - ENSG00000111785
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ric8bENSDARG00000005972Danio rerio
 RIC8BENSGALG00000029484Gallus gallus
 Ric8bENSMUSG00000035620Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RIC8A / Q9NPQ8 / RIC8 guanine nucleotide exchange factor AENSG0000017796346


Protein motifs (from Interpro)
Interpro ID Name
 IPR008376  Synembryn
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR019318  Guanine nucleotide exchange factor, Ric8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005938 cell cortex IEA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005488 binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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