ENSG00000178038


Homo sapiens

Features
Gene ID: ENSG00000178038
  
Biological name :ALS2CL
  
Synonyms : ALS2CL / ALS2 C-terminal like / Q60I27
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 46668997
Gene end: 46693704
  
Corresponding Affymetrix probe sets: 222333_at (Human Genome U133 Plus 2.0 Array)   229887_at (Human Genome U133 Plus 2.0 Array)   243276_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413223
Ensembl peptide - ENSP00000313670
Ensembl peptide - ENSP00000395749
Ensembl peptide - ENSP00000405335
NCBI entrez gene - 259173     See in Manteia.
OMIM - 612402
RefSeq - XM_017006120
RefSeq - NM_001190707
RefSeq - NM_147129
RefSeq - XM_006713091
RefSeq - XM_006713093
RefSeq - XM_006713094
RefSeq - XM_011533572
RefSeq Peptide - NP_001177636
RefSeq Peptide - NP_667340
swissprot - G5E9N5
swissprot - H7C0M4
swissprot - Q60I27
swissprot - A0A024R2U1
Ensembl - ENSG00000178038
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALS2CLENSGALG00000005430Gallus gallus
 Als2clENSMUSG00000044037Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALS2 / Q96Q42 / ALS2, alsin Rho guanine nucleotide exchange factorENSG0000000339334
P0C881 / RSPH10B / radial spoke head 10 homolog BENSG0000015502612
B2RC85 / RSPH10B2 / radial spoke head 10 homolog B2ENSG0000016940212
MORN1 / Q5T089 / MORN repeat containing 1ENSG0000011615110
RSPH1 / Q8WYR4 / radial spoke head 1 homologENSG000001601887
MORN3 / Q6PF18 / MORN repeat containing 3ENSG000001397146


Protein motifs (from Interpro)
Interpro ID Name
 IPR003123  VPS9 domain
 IPR003409  MORN motif
 IPR035899  Dbl homology (DH) domain superfamily
 IPR037191  VPS9 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IGI
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000178038 ALS2CL / Q60I27 / ALS2 C-terminal like  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr