ENSG00000178467


Homo sapiens

Features
Gene ID: ENSG00000178467
  
Biological name :P4HTM
  
Synonyms : P4HTM / prolyl 4-hydroxylase, transmembrane / Q9NXG6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 48989886
Gene end: 49007154
  
Corresponding Affymetrix probe sets: 222125_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476303
Ensembl peptide - ENSP00000477191
Ensembl peptide - ENSP00000476858
Ensembl peptide - ENSP00000341422
Ensembl peptide - ENSP00000373235
Ensembl peptide - ENSP00000398554
NCBI entrez gene - 54681     See in Manteia.
OMIM - 614584
RefSeq - NM_177938
RefSeq - NM_177939
RefSeq Peptide - NP_808807
RefSeq Peptide - NP_808808
swissprot - V9GYK5
swissprot - H7C153
swissprot - Q9NXG6
swissprot - V9GY20
swissprot - A0A0C4DGS7
Ensembl - ENSG00000178467
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 p4htmENSDARG00000075209Danio rerio
 P4HTMENSGALG00000006937Gallus gallus
 P4htmENSMUSG00000006675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045646 regulation of erythrocyte differentiation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IDA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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