ENSDARG00000075209


Danio rerio

Features
Gene ID: ENSDARG00000075209
  
Biological name :p4htm
  
Synonyms : p4htm / prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
  
Possible biological names infered from orthology : prolyl 4-hydroxylase, transmembrane / Q8BG58 / Q9NXG6
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 40730869
Gene end: 40744726
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129235
Ensembl peptide - ENSDARP00000151136
NCBI entrez gene - 799930     See in Manteia.
RefSeq - XM_001340198
swissprot - X1WG80
ZFIN ID - ZDB-GENE-110131-7
Ensembl - ENSDARG00000075209
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P4HTMENSGALG00000006937Gallus gallus
 P4HTMENSG00000178467Homo sapiens
 P4htmENSMUSG00000006675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:158254ENSDARG0000007123350


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032836 glomerular basement membrane development IMP
 biological_processGO:0039021 pronephric glomerulus development IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens opaque , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000152 retina retina disorganized , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001326 lens epithelium lens epithelium nucleus mislocalised , abnormal
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 ZFA:0001673 pronephric podocyte pronephric podocyte shape , abnormal
pronephric podocyte decreased amount , abnormal
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 ZFA:0005310 pronephric glomerular capsule pronephric glomerular capsule dilated , abnormal
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 ZFA:0005313 pronephric glomerular basement membrane pronephric glomerular basement membrane broken , abnormal
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 ZFA:0005574 lens capsule lens capsule basement membrane decreased thickness , abnormal
lens capsule basement membrane broken , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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