ENSG00000178473


Homo sapiens

Features
Gene ID: ENSG00000178473
  
Biological name :UCN3
  
Synonyms : Q969E3 / UCN3 / urocortin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p15.1
Gene start: 5365009
Gene end: 5374692
  
Corresponding Affymetrix probe sets: 1552676_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000369798
NCBI entrez gene - 114131     See in Manteia.
OMIM - 605901
RefSeq - NM_053049
RefSeq Peptide - NP_444277
swissprot - Q969E3
Ensembl - ENSG00000178473
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ucn3lENSDARG00000087241Danio rerio
 UCN3ENSGALG00000032978Gallus gallus
 Ucn3ENSMUSG00000044988Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000187  Corticotropin-releasing factor
 IPR024270  Urocortin II/III


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0031669 cellular response to nutrient levels IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0045838 positive regulation of membrane potential IEA
 biological_processGO:0051412 response to corticosterone IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043196 varicosity IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IBA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0051429 corticotropin-releasing hormone receptor binding IPI
 molecular_functionGO:0051431 corticotropin-releasing hormone receptor 2 binding IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106113 CRHR2 / Q13324 / corticotropin releasing hormone receptor 2  / complex / reaction






 

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