ENSG00000106113


Homo sapiens

Features
Gene ID: ENSG00000106113
  
Biological name :CRHR2
  
Synonyms : corticotropin releasing hormone receptor 2 / CRHR2 / Q13324
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p14.3
Gene start: 30651943
Gene end: 30700129
  
Corresponding Affymetrix probe sets: 207897_at (Human Genome U133 Plus 2.0 Array)   211510_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416620
Ensembl peptide - ENSP00000401930
Ensembl peptide - ENSP00000418722
Ensembl peptide - ENSP00000426498
Ensembl peptide - ENSP00000340943
Ensembl peptide - ENSP00000344304
Ensembl peptide - ENSP00000401241
NCBI entrez gene - 1395     See in Manteia.
OMIM - 602034
RefSeq - XM_017011752
RefSeq - NM_001202475
RefSeq - NM_001202481
RefSeq - NM_001202482
RefSeq - NM_001202483
RefSeq - NM_001883
RefSeq - XM_011515127
RefSeq - XM_011515128
RefSeq - XM_011515129
RefSeq - XM_017011751
RefSeq Peptide - NP_001189410
RefSeq Peptide - NP_001189411
RefSeq Peptide - NP_001189412
RefSeq Peptide - NP_001874
RefSeq Peptide - NP_001189404
swissprot - F2Z2M6
swissprot - Q13324
swissprot - A0A090N7T4
swissprot - C9JZM9
Ensembl - ENSG00000106113
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crhr2ENSDARG00000103704Danio rerio
 CRHR2ENSGALG00000005657Gallus gallus
 Crhr2ENSMUSG00000003476Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRHR1 / P34998 / corticotropin releasing hormone receptor 1ENSG0000012008866
LINC02210-CRHR1 / LINC02210-CRHR1 readthroughENSG0000026371544
CALCR / P30988 / calcitonin receptorENSG0000000494829
CALCRL / Q16602 / calcitonin receptor like receptorENSG0000006498928


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR003051  GPCR, family 2, corticotropin releasing factor receptor
 IPR003053  GPCR, family 2, corticotropin releasing factor receptor, type 2
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036445  GPCR family 2, extracellular hormone receptor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0071376 cellular response to corticotropin-releasing hormone stimulus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015056 corticotrophin-releasing factor receptor activity TAS


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163794 UCN / P55089 / urocortin  / complex / reaction
 ENSG00000147571 CRH / P06850 / corticotropin releasing hormone  / complex / reaction
 ENSG00000178473 UCN3 / Q969E3 / urocortin 3  / reaction / complex
 ENSG00000145040 UCN2 / Q96RP3 / urocortin 2  / complex / reaction






 

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