ENSG00000178585


Homo sapiens

Features
Gene ID: ENSG00000178585
  
Biological name :CTNNBIP1
  
Synonyms : catenin beta interacting protein 1 / CTNNBIP1 / Q9NSA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.22
Gene start: 9848276
Gene end: 9910336
  
Corresponding Affymetrix probe sets: 203081_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383696
Ensembl peptide - ENSP00000366466
Ensembl peptide - ENSP00000366468
Ensembl peptide - ENSP00000366474
NCBI entrez gene - 56998     See in Manteia.
OMIM - 607758
RefSeq - XM_017001855
RefSeq - NM_001012329
RefSeq - NM_020248
RefSeq - XM_017001853
RefSeq - XM_017001854
RefSeq Peptide - NP_001012329
RefSeq Peptide - NP_064633
swissprot - Q9NSA3
swissprot - A0A024R4D7
Ensembl - ENSG00000178585
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctnnbip1ENSDARG00000038954Danio rerio
 CTNNBIP1ENSGALG00000026306Gallus gallus
 Q9JJN6ENSMUSG00000028988Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LZIC / Q8WZA0 / leucine zipper and CTNNBIP1 domain containingENSG0000016244136


Protein motifs (from Interpro)
Interpro ID Name
 IPR009428  Beta-catenin-interacting ICAT
 IPR036911  Beta-catenin-interacting ICAT superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IBA
 biological_processGO:0002528 regulation of vascular permeability involved in acute inflammatory response IMP
 biological_processGO:0009952 anterior/posterior pattern specification IBA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IBA
 biological_processGO:0031333 negative regulation of protein complex assembly IEA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0045657 positive regulation of monocyte differentiation IMP
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0072201 negative regulation of mesenchymal cell proliferation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030877 beta-catenin destruction complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0070016 armadillo repeat domain binding IPI


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168036 CTNNB1 / P35222 / catenin beta 1  / reaction / complex






 

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