ENSG00000178860


Homo sapiens

Features
Gene ID: ENSG00000178860
  
Biological name :MSC
  
Synonyms : MSC / musculin / O60682
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q13.3
Gene start: 71841549
Gene end: 71844468
  
Corresponding Affymetrix probe sets: 209928_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321445
NCBI entrez gene - 9242     See in Manteia.
OMIM - 603628
RefSeq - NM_005098
RefSeq Peptide - NP_005089
swissprot - O60682
Ensembl - ENSG00000178860
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mscENSDARG00000110016Danio rerio
 MSCENSGALG00000037777Gallus gallus
 MscENSMUSG00000025930Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TCF21 / O43680 / transcription factor 21ENSG0000011852652
TCF24 / Q7RTU0 / transcription factor 24ENSG0000026178723
TCF23 / Q7RTU1 / transcription factor 23ENSG0000016379222


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0014707 branchiomeric skeletal muscle development IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060539 diaphragm development IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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