ENSG00000178996


Homo sapiens

Features
Gene ID: ENSG00000178996
  
Biological name :SNX18
  
Synonyms : Q96RF0 / SNX18 / sorting nexin 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q11.2
Gene start: 54517759
Gene end: 54546585
  
Corresponding Affymetrix probe sets: 1552828_at (Human Genome U133 Plus 2.0 Array)   226683_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317332
Ensembl peptide - ENSP00000342276
Ensembl peptide - ENSP00000370817
NCBI entrez gene - 112574     See in Manteia.
RefSeq - NM_001145427
RefSeq - NM_001102575
RefSeq - NM_052870
RefSeq Peptide - NP_001096045
RefSeq Peptide - NP_001138899
RefSeq Peptide - NP_443102
swissprot - Q96RF0
Ensembl - ENSG00000178996
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx18aENSDARG00000067713Danio rerio
 snx18bENSDARG00000044246Danio rerio
 SNX18ENSGALG00000014914Gallus gallus
 Snx18ENSMUSG00000042364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX33 / Q8WV41 / sorting nexin 33ENSG0000017354843
SNX9 / Q9Y5X1 / sorting nexin 9ENSG0000013034029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001683  Phox homologous domain
 IPR014536  Sorting nexin 9 family
 IPR019497  Sorting nexin protein, WASP-binding domain
 IPR027267  AH/BAR domain superfamily
 IPR035557  Sorting nexin-18, SH3 domain
 IPR035703  SNX18, PX domain
 IPR036028  SH3-like domain superfamily
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport IMP
 biological_processGO:0036089 cleavage furrow formation IMP
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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