ENSG00000179284


Homo sapiens

Features
Gene ID: ENSG00000179284
  
Biological name :DAND5
  
Synonyms : DAND5 / DAN domain BMP antagonist family member 5 / Q8N907
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12965159
Gene end: 12974762
  
Corresponding Affymetrix probe sets: 1562772_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323155
Ensembl peptide - ENSP00000467806
NCBI entrez gene - 199699     See in Manteia.
OMIM - 609068
RefSeq - NM_152654
RefSeq Peptide - NP_689867
swissprot - Q8N907
swissprot - K7EQF6
Ensembl - ENSG00000179284
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dand5ENSDARG00000036471Danio rerio
 Dand5ENSMUSG00000053226Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CER1 / O95813 / cerberus 1, DAN family BMP antagonistENSG0000014786930


Protein motifs (from Interpro)
Interpro ID Name
 IPR004133  DAN
 IPR016860  Cerberus
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003140 determination of left/right asymmetry in lateral mesoderm IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0003283 atrial septum development IEA
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IBA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0035582 sequestering of BMP in extracellular matrix IBA
 biological_processGO:0038101 sequestering of nodal from receptor via nodal binding IEA
 biological_processGO:0061371 determination of heart left/right asymmetry IEA
 biological_processGO:1900108 negative regulation of nodal signaling pathway IEA
 biological_processGO:1900176 negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry IBA
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0016015 morphogen activity IEA


Pathways (from Reactome)
Pathway description
Signaling by NODAL
Regulation of signaling by NODAL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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