ENSG00000179588


Homo sapiens

Features
Gene ID: ENSG00000179588
  
Biological name :ZFPM1
  
Synonyms : Q8IX07 / ZFPM1 / zinc finger protein, FOG family member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.2
Gene start: 88453317
Gene end: 88537016
  
Corresponding Affymetrix probe sets: 237463_at (Human Genome U133 Plus 2.0 Array)   242282_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000326630
Ensembl peptide - ENSP00000484216
Ensembl peptide - ENSP00000482796
Ensembl peptide - ENSP00000480412
NCBI entrez gene - 161882     See in Manteia.
OMIM - 601950
RefSeq - XM_011522912
RefSeq - XM_017022982
RefSeq - XM_011522917
RefSeq - NM_153813
RefSeq - XM_011522914
RefSeq Peptide - NP_722520
swissprot - Q8IX07
swissprot - A0A087X1H8
swissprot - A0A087WWQ0
swissprot - A0A087WZP1
Ensembl - ENSG00000179588
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfpm1ENSDARG00000041572Danio rerio
 ZFPM1ENSGALG00000006099Gallus gallus
 Zfpm1ENSMUSG00000049577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZFPM2 / Q8WW38 / zinc finger protein, FOG family member 2ENSG0000016994632


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR034731  Zinc finger CCHC FOG-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002295 T-helper cell lineage commitment IC
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0003181 atrioventricular valve morphogenesis IEA
 biological_processGO:0003192 mitral valve formation IEA
 biological_processGO:0003195 tricuspid valve formation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0010724 regulation of definitive erythrocyte differentiation IMP
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0030219 megakaryocyte differentiation IEA
 biological_processGO:0030220 platelet formation IGI
 biological_processGO:0030851 granulocyte differentiation IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032642 regulation of chemokine production IEA
 biological_processGO:0035162 embryonic hemopoiesis IEA
 biological_processGO:0035855 megakaryocyte development IEA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process IDA
 biological_processGO:0045403 negative regulation of interleukin-4 biosynthetic process IDA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045652 regulation of megakaryocyte differentiation TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0055008 cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060318 definitive erythrocyte differentiation IEA
 biological_processGO:0060319 primitive erythrocyte differentiation IEA
 biological_processGO:0060377 negative regulation of mast cell differentiation IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060413 atrial septum morphogenesis IEA
 biological_processGO:0071733 transcriptional activation by promoter-enhancer looping IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IPI
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000102145 GATA1 / P15976 / GATA binding protein 1  / complex






 

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