ENSG00000179598


Homo sapiens

Features
Gene ID: ENSG00000179598
  
Biological name :PLD6
  
Synonyms : phospholipase D family member 6 / PLD6 / Q8N2A8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p11.2
Gene start: 17200995
Gene end: 17206315
  
Corresponding Affymetrix probe sets: 227037_at (Human Genome U133 Plus 2.0 Array)   244430_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317177
NCBI entrez gene - 201164     See in Manteia.
OMIM - 614960
RefSeq - NM_178836
RefSeq - XM_017024310
RefSeq Peptide - NP_849158
swissprot - Q8N2A8
Ensembl - ENSG00000179598
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pld6ENSDARG00000059951Danio rerio
 Pld6ENSMUSG00000043648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR025202  Phospholipase D-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0008053 mitochondrial fusion IMP
 biological_processGO:0010636 positive regulation of mitochondrial fusion IDA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030719 P granule organization IEA
 biological_processGO:0034587 piRNA metabolic process IEA
 biological_processGO:0043046 DNA methylation involved in gamete generation IEA
 biological_processGO:0051321 meiotic cell cycle ISS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035755 cardiolipin hydrolase activity TAS
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PG
Synthesis of PA
PIWI-interacting RNA (piRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000179598 PLD6 / Q8N2A8 / phospholipase D family member 6  / complex






 

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