ENSG00000180667


Homo sapiens

Features
Gene ID: ENSG00000180667
  
Biological name :YOD1
  
Synonyms : Q5VVQ6 / YOD1 / YOD1 deubiquitinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 207043849
Gene end: 207052980
  
Corresponding Affymetrix probe sets: 215150_at (Human Genome U133 Plus 2.0 Array)   227309_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000326813
Ensembl peptide - ENSP00000356051
NCBI entrez gene - 55432     See in Manteia.
OMIM - 612023
RefSeq - NM_001276320
RefSeq - NM_018566
RefSeq Peptide - NP_001263249
RefSeq Peptide - NP_061036
swissprot - Q5VVQ6
Ensembl - ENSG00000180667
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 yod1ENSDARG00000008542Danio rerio
 YOD1ENSGALG00000037597Gallus gallus
 Yod1ENSMUSG00000046404Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain
 IPR013087  Zinc finger C2H2-type
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0016236 macroautophagy IMP
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IMP
 biological_processGO:0035523 protein K29-linked deubiquitination IDA
 biological_processGO:0035871 protein K11-linked deubiquitination IMP
 biological_processGO:0070536 protein K63-linked deubiquitination IMP
 biological_processGO:0071108 protein K48-linked deubiquitination IMP
 biological_processGO:1904153 negative regulation of retrograde protein transport, ER to cytosol IEA
 biological_processGO:1990167 protein K27-linked deubiquitination IDA
 biological_processGO:1990168 protein K33-linked deubiquitination IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061578 Lys63-specific deubiquitinase activity TAS
 molecular_functionGO:1904265 ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol IMP
 molecular_functionGO:1990380 Lys48-specific deubiquitinase activity TAS


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165280 VCP / P55072 / valosin containing protein  / complex / reaction






 

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