ENSG00000180815


Homo sapiens

Features
Gene ID: ENSG00000180815
  
Biological name :MAP3K15
  
Synonyms : MAP3K15 / mitogen-activated protein kinase kinase kinase 15 / Q6ZN16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.12
Gene start: 19360056
Gene end: 19515261
  
Corresponding Affymetrix probe sets: 242581_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352093
Ensembl peptide - ENSP00000345629
NCBI entrez gene - 389840     See in Manteia.
OMIM - 300820
RefSeq - XM_017029511
RefSeq - NM_001001671
RefSeq - XM_011545508
RefSeq - XM_011545510
RefSeq - XM_011545511
RefSeq - XM_011545507
RefSeq Peptide - NP_001001671
swissprot - Q6ZN16
swissprot - A0A140T8W5
Ensembl - ENSG00000180815
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map3k15ENSDARG00000013310Danio rerio
 MAP3K15ENSGALG00000016426Gallus gallus
 A2AQW0ENSMUSG00000031303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP3K5 / Q99683 / mitogen-activated protein kinase kinase kinase 5ENSG0000019744258
MAP3K6 / O95382 / mitogen-activated protein kinase kinase kinase 6ENSG0000014273343


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR025136  Domain of unknown function DUF4071


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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