ENSG00000180817


Homo sapiens

Features
Gene ID: ENSG00000180817
  
Biological name :PPA1
  
Synonyms : PPA1 / pyrophosphatase (inorganic) 1 / Q15181
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q22.1
Gene start: 70202830
Gene end: 70233911
  
Corresponding Affymetrix probe sets: 217848_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362327
Ensembl peptide - ENSP00000362329
Ensembl peptide - ENSP00000486162
NCBI entrez gene - 5464     See in Manteia.
OMIM - 179030
RefSeq - NM_021129
RefSeq Peptide - NP_066952
swissprot - Q15181
swissprot - Q5SQT6
swissprot - V9HWB5
Ensembl - ENSG00000180817
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppa1aENSDARG00000099933Danio rerio
 ppa1bENSDARG00000030441Danio rerio
 PPA1ENSGALG00000004442Gallus gallus
 Ppa1ENSMUSG00000020089Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPA2 / Q9H2U2 / pyrophosphatase (inorganic) 2ENSG0000013877761


Protein motifs (from Interpro)
Interpro ID Name
 IPR008162  Inorganic pyrophosphatase
 IPR036649  Inorganic pyrophosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006418 tRNA aminoacylation for protein translation TAS
 biological_processGO:0006796 phosphate-containing compound metabolic process IEA
 biological_processGO:0071344 diphosphate metabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004427 inorganic diphosphatase activity IEA
 molecular_functionGO:0016462 pyrophosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cytosolic tRNA aminoacylation
Pyrophosphate hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000180817 PPA1 / Q15181 / pyrophosphatase (inorganic) 1  / complex






 

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