ENSG00000180957


Homo sapiens

Features
Gene ID: ENSG00000180957
  
Biological name :PITPNB
  
Synonyms : P48739 / phosphatidylinositol transfer protein beta / PITPNB
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.1
Gene start: 27851669
Gene end: 27920134
  
Corresponding Affymetrix probe sets: 202522_at (Human Genome U133 Plus 2.0 Array)   235985_at (Human Genome U133 Plus 2.0 Array)   244826_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000334738
Ensembl peptide - ENSP00000487693
Ensembl peptide - ENSP00000406542
Ensembl peptide - ENSP00000405179
Ensembl peptide - ENSP00000403675
Ensembl peptide - ENSP00000321266
NCBI entrez gene - 23760     See in Manteia.
OMIM - 606876
RefSeq - XM_017028707
RefSeq - NM_001284277
RefSeq - NM_001284278
RefSeq - NM_012399
RefSeq - XM_011530052
RefSeq Peptide - NP_001271207
RefSeq Peptide - NP_036531
RefSeq Peptide - NP_001271206
swissprot - P48739
swissprot - A0A0A0MSW4
swissprot - B3KYB7
swissprot - B3KYB6
Ensembl - ENSG00000180957
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pitpnbENSDARG00000036005Danio rerio
 PITPNBENSGALG00000005654Gallus gallus
 P53811ENSMUSG00000050017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PITPNA / Q00169 / phosphatidylinositol transfer protein alphaENSG0000017423875
Q9BZ72 / PITPNM2 / phosphatidylinositol transfer protein membrane associated 2ENSG0000009097543
O00562 / PITPNM1 / phosphatidylinositol transfer protein membrane associated 1ENSG0000011069742
Q9UKF7 / PITPNC1 / phosphatidylinositol transfer protein, cytoplasmic 1ENSG0000015421739
Q9BZ71 / PITPNM3 / PITPNM family member 3ENSG000000916222


Protein motifs (from Interpro)
Interpro ID Name
 IPR001666  Phosphatidylinositol transfer protein
 IPR023393  START-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process NAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0006997 nucleus organization TAS
 biological_processGO:0015914 phospholipid transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005548 phospholipid transporter activity IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008525 phosphatidylcholine transporter activity IDA
 molecular_functionGO:0008526 phosphatidylinositol transporter activity IDA
 molecular_functionGO:0031210 phosphatidylcholine binding IDA
 molecular_functionGO:0035091 phosphatidylinositol binding IDA


Pathways (from Reactome)
Pathway description
PI and PC transport between ER and Golgi membranes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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