ENSG00000181867


Homo sapiens

Features
Gene ID: ENSG00000181867
  
Biological name :FTMT
  
Synonyms : ferritin mitochondrial / FTMT / Q8N4E7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q23.1
Gene start: 121851955
Gene end: 121852833
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000313691
NCBI entrez gene - 94033     See in Manteia.
OMIM - 608847
RefSeq - NM_177478
RefSeq Peptide - NP_803431
swissprot - Q8N4E7
Ensembl - ENSG00000181867
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fth1aENSDARG00000015551Danio rerio
 fth1bENSDARG00000007975Danio rerio
 FtmtENSMUSG00000024510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FTH1 / P02794 / ferritin heavy chain 1ENSG0000016799660
FTHL17 / Q9BXU8 / ferritin heavy chain like 17ENSG0000013244648
FTL / P02792 / ferritin light chainENSG0000008708639


Protein motifs (from Interpro)
Interpro ID Name
 IPR001519  Ferritin
 IPR008331  Ferritin/DPS protein domain
 IPR009040  Ferritin-like diiron domain
 IPR009078  Ferritin-like superfamily
 IPR012347  Ferritin-like
 IPR014034  Ferritin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006826 iron ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis IDA
 biological_processGO:0006880 intracellular sequestering of iron ion IBA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0051349 positive regulation of lyase activity IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1904231 positive regulation of succinate dehydrogenase activity IGI
 biological_processGO:1904234 positive regulation of aconitate hydratase activity IGI
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0004322 ferroxidase activity TAS
 molecular_functionGO:0005506 iron ion binding IBA
 molecular_functionGO:0008199 ferric iron binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000181867 FTMT / Q8N4E7 / ferritin mitochondrial  / complex






 

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